Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1.

Schwitzgebel, Valerie M; Mamin, Aline; Brun, Thierry; Ritz-Laser, Beate; Zaiko, Maia; Maret, Alexandre; Jornayvaz, Francois R; Theintz, Gerald E; Michielin, Olivier; Melloul, Danielle; Philippe, Jacques

Schwitzgebel, Valerie M; Mamin, Aline; Brun, Thierry; Ritz-Laser, Beate; Zaiko, Maia; Maret, Alexandre; Jornayvaz, Francois R; Theintz, Gerald E; Michielin, Olivier; Melloul, Danielle; Philippe, Jacques.

Affiliation

Schwitzgebel VM; Pediatric Endocrinology and Diabetology, Geneva University Hospital, CH-1211 Geneva, Switzerland. valerie.schwitzgebel@medcli.unige.ch

J Clin Endocrinol Metab ; 88(9): 4398-406, 2003 Sep.

Article in En | MEDLINE | ID: mdl-12970316

Subject(s)

Homeodomain Proteins; Mutation/physiology; Pancreas/abnormalities; Pancreas/growth & development; Trans-Activators/genetics; Trans-Activators/metabolism; Amino Acid Sequence; Animals; Blotting, Western; Cells, Cultured; Cricetinae; DNA/genetics; Electrophoretic Mobility Shift Assay; Genes, Reporter/genetics; Glucose Tolerance Test; Green Fluorescent Proteins; Half-Life; Humans; Isotope Labeling; Luminescent Proteins/biosynthesis; Luminescent Proteins/genetics; Molecular Sequence Data; Mutagenesis; Plasmids/genetics; Precipitin Tests; Reverse Transcriptase Polymerase Chain Reaction; Trans-Activators/chemistry; Transcriptional Activation/genetics; Transfection; Translocation, Genetic/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Pancreas / Trans-Activators / Homeodomain Proteins / Mutation Limits: Animals / Humans Language: En Journal: J Clin Endocrinol Metab Year: 2003 Type: Article Affiliation country: Switzerland

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