Endothelin-1 as a luteinization inhibitor: inhibition of rat granulosa cell progesterone accumulation via selective modulation of key steroidogenic steps affecting both progesterone formation and degradation.

Tedeschi, C; Hazum, E; Kokia, E; Ricciarelli, E; Adashi, E Y; Payne, D W

Tedeschi, C; Hazum, E; Kokia, E; Ricciarelli, E; Adashi, E Y; Payne, D W.

Affiliation

Tedeschi C; University of Maryland School of Medicine, Department of Obstetrics Gynecology, Baltimore.

Endocrinology ; 131(5): 2476-8, 1992 Nov.

Article in En | MEDLINE | ID: mdl-1425445

Subject(s)

Endothelins/pharmacology; Granulosa Cells/metabolism; Lutein/antagonists & inhibitors; Progesterone/metabolism; 20-alpha-Dihydroprogesterone/metabolism; 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme/antagonists & inhibitors; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone/pharmacology; Granulosa Cells/chemistry; Granulosa Cells/cytology; Pregnanediol/metabolism; Pregnenolone/metabolism; Progesterone/analysis; Rats

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Collection: 01-internacional Database: MEDLINE Main subject: Progesterone / Lutein / Endothelins / Granulosa Cells Limits: Animals Language: En Journal: Endocrinology Year: 1992 Type: Article

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