The routine microbiological screening of central venous catheters in home parenteral nutrition patients.
Clin Nutr
; 23(2): 171-5, 2004 Apr.
Article
in En
| MEDLINE
| ID: mdl-15030956
ABSTRACT
BACKGROUND & AIMS:
Catheter-related bloodstream infection (CRBSI) is a major complication for patients receiving home parenteral nutrition (HTPN). Endoluminal sampling techniques allow the diagnosis of CRBSI without catheter removal and may allow the screening of asymptomatic patients.METHODS:
Over a 5-year period, patients receiving HTPN were offered screening on a 3 monthly basis. All patients had tunnelled cuffed Hickman lines. All were asymptomatic at the time of screening, which took the form of either endoluminal brushing or quantitative cultures on through-line blood.RESULTS:
Thirty-two patients were suitable for inclusion within the study period (10 male, median age 51 (iqr 46-61)) years with 30 of these having a least one screening performed. Four had positive screening results and underwent appropriate treatment. Of the remainder, 12 presented with at least one clinical episode of CRBSI and 14 had neither clinical CRBSI nor a positive screening result. The combined clinical and screening CRBSI rate was 0.39 episodes per catheter year.CONCLUSION:
Although routine microbiological catheter screening can detect subclinical infections in HTPN patients the positive rate is low with the majority of patients still presenting clinical. Identification of higher risk patients and appropriate alterations to screening frequency may improve its value further.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Catheterization, Central Venous
/
Parenteral Nutrition, Home Total
/
Sepsis
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Screening_studies
Limits:
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Clin Nutr
Year:
2004
Type:
Article
Affiliation country:
United kingdom