A large-scale RNAi screen in human cells identifies new components of the p53 pathway.

Berns, Katrien; Hijmans, E Marielle; Mullenders, Jasper; Brummelkamp, Thijn R; Velds, Arno; Heimerikx, Mike; Kerkhoven, Ron M; Madiredjo, Mandy; Nijkamp, Wouter; Weigelt, Britta; Agami, Reuven; Ge, Wei; Cavet, Guy; Linsley, Peter S; Beijersbergen, Roderick L; Bernards, René

Berns, Katrien; Hijmans, E Marielle; Mullenders, Jasper; Brummelkamp, Thijn R; Velds, Arno; Heimerikx, Mike; Kerkhoven, Ron M; Madiredjo, Mandy; Nijkamp, Wouter; Weigelt, Britta; Agami, Reuven; Ge, Wei; Cavet, Guy; Linsley, Peter S; Beijersbergen, Roderick L; Bernards, René.

Affiliation

Berns K; Division of Molecular Carcinogenesis and Center for Biomedical Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

Nature ; 428(6981): 431-7, 2004 Mar 25.

Article in En | MEDLINE | ID: mdl-15042092

Subject(s)

Gene Library; RNA Interference; Tumor Suppressor Protein p53/metabolism; Cell Division; Cell Line, Tumor; Cloning, Molecular; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins/genetics; Cyclins/metabolism; Down-Regulation; Fibroblasts; Genetic Vectors/genetics; Humans; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; Reproducibility of Results; Retroviridae/genetics; Tumor Suppressor Protein p14ARF/metabolism; Tumor Suppressor Protein p53/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Gene Library / Tumor Suppressor Protein p53 / RNA Interference Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nature Year: 2004 Type: Article Affiliation country: Netherlands

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