Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial.

Keystone, Edward C; Kavanaugh, Arthur F; Sharp, John T; Tannenbaum, Hyman; Hua, Ye; Teoh, Leah S; Fischkoff, Steven A; Chartash, Elliot K

Keystone, Edward C; Kavanaugh, Arthur F; Sharp, John T; Tannenbaum, Hyman; Hua, Ye; Teoh, Leah S; Fischkoff, Steven A; Chartash, Elliot K.

Affiliation

Keystone EC; University of Toronto, Toronto, Ontario M5G 1X5, Canada.

Arthritis Rheum ; 50(5): 1400-11, 2004 May.

Article in En | MEDLINE | ID: mdl-15146409

Subject(s)

Antibodies, Monoclonal/administration & dosage; Antirheumatic Agents/administration & dosage; Arthritis, Rheumatoid/diagnostic imaging; Arthritis, Rheumatoid/drug therapy; Methotrexate/administration & dosage; Activities of Daily Living; Adalimumab; Adult; Aged; Antibodies, Monoclonal/adverse effects; Antibodies, Monoclonal, Humanized; Antirheumatic Agents/adverse effects; Drug Therapy, Combination; Female; Humans; Male; Methotrexate/adverse effects; Middle Aged; Placebos; Quality of Life; Radiography; Recovery of Function; Treatment Outcome; Tumor Necrosis Factor-alpha/antagonists & inhibitors; Tumor Necrosis Factor-alpha/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Methotrexate / Antirheumatic Agents / Antibodies, Monoclonal Type of study: Clinical_trials / Diagnostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Arthritis Rheum Year: 2004 Type: Article Affiliation country: Canada

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