Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo.

Reed, John R; Vukmanovic-Stejic, Milica; Fletcher, Jean M; Soares, Maria Vieira D; Cook, Joanne E; Orteu, Catherine H; Jackson, Sarah E; Birch, Katie E; Foster, Graham R; Salmon, Mike; Beverley, Peter C L; Rustin, Malcolm H A; Akbar, Arne N

Reed, John R; Vukmanovic-Stejic, Milica; Fletcher, Jean M; Soares, Maria Vieira D; Cook, Joanne E; Orteu, Catherine H; Jackson, Sarah E; Birch, Katie E; Foster, Graham R; Salmon, Mike; Beverley, Peter C L; Rustin, Malcolm H A; Akbar, Arne N.

Affiliation

Reed JR; Dept. of Immunology and Molecular Pathology, Div. of Infection and Immunity, University College London, 46 Cleveland St., London W1T 4JF, England, UK.

J Exp Med ; 199(10): 1433-43, 2004 May 17.

Article in En | MEDLINE | ID: mdl-15148341

Subject(s)

Immunologic Memory/immunology; T-Lymphocytes/immunology; Telomerase/drug effects; Telomerase/immunology; Telomere/genetics; BCG Vaccine/immunology; CD4-Positive T-Lymphocytes/immunology; Cells, Cultured; Enzyme Inhibitors/pharmacology; Humans; In Situ Hybridization, Fluorescence; Lymphocyte Activation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Telomere / Telomerase / Immunologic Memory Limits: Humans Language: En Journal: J Exp Med Year: 2004 Type: Article Affiliation country: United kingdom

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