Modulation of ovalbumin-induced Th2 responses by second-generation immunomodulatory oligonucleotides in mice.

Zhu, Fu-Gang; Kandimalla, Ekambar R; Yu, Dong; Tang, Jimmy X; Agrawal, Sudhir

Zhu, Fu-Gang; Kandimalla, Ekambar R; Yu, Dong; Tang, Jimmy X; Agrawal, Sudhir.

Affiliation

Zhu FG; Hybridon, Inc., 345 Vassar Street, Cambridge, MA 02139, USA.

Int Immunopharmacol ; 4(7): 851-62, 2004 Jul.

Article in En | MEDLINE | ID: mdl-15182725

Subject(s)

Deoxyguanosine/analogs & derivatives; Deoxyguanosine/pharmacology; Immunologic Factors/pharmacology; Lung/drug effects; Oligodeoxyribonucleotides/pharmacology; Spleen/drug effects; Th2 Cells/immunology; Animals; Cells, Cultured; Cytokines/biosynthesis; Deoxyguanosine/chemical synthesis; Drug Combinations; Female; Immunoglobulin E/biosynthesis; Immunoglobulin E/blood; Immunoglobulin G/biosynthesis; Immunoglobulin G/blood; Immunologic Memory; Interferon-gamma/biosynthesis; Lung/immunology; Lung/pathology; Mice; Mice, Inbred BALB C; Oligodeoxyribonucleotides/chemical synthesis; Ovalbumin/administration & dosage; Ovalbumin/immunology; Pneumonia/etiology; Pneumonia/prevention & control; Spleen/cytology; Spleen/immunology; Th2 Cells/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Oligodeoxyribonucleotides / Spleen / Th2 Cells / Deoxyguanosine / Immunologic Factors / Lung Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Int Immunopharmacol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Year: 2004 Type: Article Affiliation country: United States

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