Cells release prions in association with exosomes.

Fevrier, Benoit; Vilette, Didier; Archer, Fabienne; Loew, Damarys; Faigle, Wolfgang; Vidal, Michel; Laude, Hubert; Raposo, Graça

Fevrier, Benoit; Vilette, Didier; Archer, Fabienne; Loew, Damarys; Faigle, Wolfgang; Vidal, Michel; Laude, Hubert; Raposo, Graça.

Affiliation

Fevrier B; Centre National de la Recherche Scientifique, Unité Mixte de Recherche 144, Institut Curie, 75005 Paris, France.

Proc Natl Acad Sci U S A ; 101(26): 9683-8, 2004 Jun 29.

Article in En | MEDLINE | ID: mdl-15210972

Subject(s)

Exocytosis; Prion Diseases/metabolism; Prions/metabolism; Secretory Vesicles/metabolism; Amyloid/deficiency; Amyloid/genetics; Amyloid/metabolism; Animals; Biological Assay; Blotting, Western; Brain/drug effects; Brain/metabolism; Cell Extracts; Cell Line; Cell Membrane/metabolism; Culture Media, Conditioned/chemistry; Culture Media, Conditioned/metabolism; Culture Media, Conditioned/pharmacology; Endosomes/metabolism; Extracellular Space/metabolism; Gene Deletion; Intracellular Membranes/metabolism; Mass Spectrometry; Mice; Mice, Transgenic; PrPSc Proteins/metabolism; Prion Diseases/transmission; Prion Proteins; Protein Precursors/deficiency; Protein Precursors/genetics; Protein Precursors/metabolism; Sheep

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prions / Prion Diseases / Secretory Vesicles / Exocytosis Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2004 Type: Article Affiliation country: France

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