Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality.

Hopkins, Kevin M; Auerbach, Wojtek; Wang, Xiang Yuan; Hande, M Prakash; Hang, Haiying; Wolgemuth, Debra J; Joyner, Alexandra L; Lieberman, Howard B

Hopkins, Kevin M; Auerbach, Wojtek; Wang, Xiang Yuan; Hande, M Prakash; Hang, Haiying; Wolgemuth, Debra J; Joyner, Alexandra L; Lieberman, Howard B.

Affiliation

Hopkins KM; Center for Radiological Research, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

Mol Cell Biol ; 24(16): 7235-48, 2004 Aug.

Article in En | MEDLINE | ID: mdl-15282322

Subject(s)

Cell Cycle Proteins/metabolism; DNA Damage; Embryo, Mammalian/physiology; Gene Deletion; Animals; Apoptosis/physiology; Cell Cycle/physiology; Cell Cycle Proteins/genetics; Cells, Cultured; Chromosome Aberrations; Embryo, Mammalian/anatomy & histology; Gene Expression Regulation; Genes, cdc; Genomic Instability; Humans; Hydroxyurea/pharmacology; In Situ Nick-End Labeling; Mice; Mice, Knockout; Nucleic Acid Synthesis Inhibitors/pharmacology; Radiation, Ionizing; Stem Cells/cytology; Stem Cells/drug effects; Stem Cells/physiology; Stem Cells/radiation effects; Survival Rate

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Gene Deletion / Cell Cycle Proteins / Embryo, Mammalian Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Mol Cell Biol Year: 2004 Type: Article Affiliation country: United States

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