Testosterone 1 beta-hydroxylation by human cytochrome P450 3A4.

Krauser, Joel A; Voehler, Markus; Tseng, Li-Hong; Schefer, Alexandre B; Godejohann, Markus; Guengerich, F Peter

Krauser, Joel A; Voehler, Markus; Tseng, Li-Hong; Schefer, Alexandre B; Godejohann, Markus; Guengerich, F Peter.

Affiliation

Krauser JA; Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, USA.

Eur J Biochem ; 271(19): 3962-9, 2004 Oct.

Article in En | MEDLINE | ID: mdl-15373842

Subject(s)

Cytochrome P-450 Enzyme System/metabolism; Microsomes, Liver/enzymology; Testosterone/metabolism; Animals; Baculoviridae/genetics; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Humans; Hydroxylation; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microsomes, Liver/drug effects; NAD/metabolism; NADP/metabolism; Oxidation-Reduction

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Collection: 01-internacional Database: MEDLINE Main subject: Testosterone / Microsomes, Liver / Cytochrome P-450 Enzyme System Limits: Animals / Humans Language: En Journal: Eur J Biochem Year: 2004 Type: Article Affiliation country: United States

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