Formation of a complex of the catalytic subunit of pyruvate dehydrogenase phosphatase isoform 1 (PDP1c) and the L2 domain forms a Ca2+ binding site and captures PDP1c as a monomer.

Turkan, Ali; Hiromasa, Yasuaki; Roche, Thomas E

Turkan, Ali; Hiromasa, Yasuaki; Roche, Thomas E.

Affiliation

Turkan A; Department of Biochemistry, Kansas State University, Manhattan, Kansas 66506, USA.

Biochemistry ; 43(47): 15073-85, 2004 Nov 30.

Article in En | MEDLINE | ID: mdl-15554715

Subject(s)

Calcium/metabolism; Isoenzymes/metabolism; Protein Subunits/metabolism; Pyruvate Dehydrogenase (Lipoamide)-Phosphatase/metabolism; Animals; Binding Sites; Buffers; Calorimetry; Catalytic Domain; Cattle; Dose-Response Relationship, Drug; Egtazic Acid/chemistry; Enzyme Activation/drug effects; Gels; Humans; Isoenzymes/chemistry; Magnesium/pharmacology; Models, Chemical; Protein Binding; Protein Structure, Tertiary; Protein Subunits/chemistry; Pyruvate Dehydrogenase (Lipoamide)-Phosphatase/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Calcium / Pyruvate Dehydrogenase (Lipoamide)-Phosphatase / Protein Subunits / Isoenzymes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Biochemistry Year: 2004 Type: Article Affiliation country: United States

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