Synthesis and evaluation of double bond substituted combretastatins.

Hadfield, John A; Gaukroger, Keira; Hirst, Nicholas; Weston, Anna P; Lawrence, Nicholas J; McGown, Alan T

Hadfield, John A; Gaukroger, Keira; Hirst, Nicholas; Weston, Anna P; Lawrence, Nicholas J; McGown, Alan T.

Affiliation

Hadfield JA; Centre for Molecular Drug Design, Cockcroft Building, University of Salford, Manchester M5 4WT, UK. j.a.hadfield@salford.ac.uk

Eur J Med Chem ; 40(6): 529-41, 2005 Jun.

Article in En | MEDLINE | ID: mdl-15922837

Subject(s)

Antineoplastic Agents/chemical synthesis; Antineoplastic Agents/pharmacology; Bibenzyls/chemical synthesis; Bibenzyls/pharmacology; Stilbenes/chemical synthesis; Stilbenes/pharmacology; Amides/chemical synthesis; Amides/chemistry; Amides/pharmacology; Antineoplastic Agents/chemistry; Bibenzyls/chemistry; Cell Cycle/drug effects; Cell Survival/drug effects; Epoxy Compounds/chemical synthesis; Epoxy Compounds/chemistry; Epoxy Compounds/pharmacology; Formazans/chemistry; Humans; Inhibitory Concentration 50; K562 Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Spectrophotometry, Ultraviolet; Stilbenes/chemistry; Tetrazolium Salts/chemistry; Tubulin/metabolism; Tubulin Modulators

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Collection: 01-internacional Database: MEDLINE Main subject: Stilbenes / Bibenzyls / Antineoplastic Agents Limits: Humans Language: En Journal: Eur J Med Chem Year: 2005 Type: Article

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