High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx.

Maestro, R; Dolcetti, R; Gasparotto, D; Doglioni, C; Pelucchi, S; Barzan, L; Grandi, E; Boiocchi, M

Maestro, R; Dolcetti, R; Gasparotto, D; Doglioni, C; Pelucchi, S; Barzan, L; Grandi, E; Boiocchi, M.

Affiliation

Maestro R; Division of Experimental Oncology 1, Centro di Riferimento Oncologico, Aviano (PN), Italy.

Oncogene ; 7(6): 1159-66, 1992 Jun.

Article in En | MEDLINE | ID: mdl-1594246

Subject(s)

Carcinoma, Squamous Cell/genetics; Genes, p53; Laryngeal Neoplasms/genetics; Mutation; Tumor Suppressor Protein p53/genetics; Antibodies, Monoclonal; Base Sequence; Blotting, Southern; Carcinoma, Squamous Cell/pathology; DNA, Neoplasm/genetics; DNA, Neoplasm/isolation & purification; Exons; Humans; Immunohistochemistry; Laryngeal Neoplasms/pathology; Molecular Sequence Data; Molecular Weight; Oligodeoxyribonucleotides; Polymerase Chain Reaction/methods; RNA, Neoplasm/genetics; RNA, Neoplasm/isolation & purification; Restriction Mapping; Smoking; Tumor Suppressor Protein p53/analysis; Tumor Suppressor Protein p53/biosynthesis

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Laryngeal Neoplasms / Genes, p53 / Tumor Suppressor Protein p53 / Mutation Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 1992 Type: Article Affiliation country: Italy

Search on Google

XML

PubMed Links