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Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization.
Deng, James Z; McMasters, Daniel R; Rabbat, Philippe M A; Williams, Peter D; Coburn, Craig A; Yan, Youwei; Kuo, Lawrence C; Lewis, S Dale; Lucas, Bobby J; Krueger, Julie A; Strulovici, Berta; Vacca, Joseph P; Lyle, Terry A; Burgey, Christopher S.
Affiliation
  • Deng JZ; Department of Medicinal Chemistry, Merck Research Laboratories, West Point, PA 19486, USA.
Bioorg Med Chem Lett ; 15(20): 4411-6, 2005 Oct 15.
Article in En | MEDLINE | ID: mdl-16137886
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Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Antithrombins / Factor Xa Inhibitors Type of study: Prognostic_studies Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2005 Type: Article Affiliation country: United States
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Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Antithrombins / Factor Xa Inhibitors Type of study: Prognostic_studies Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2005 Type: Article Affiliation country: United States