Evaluation of Salmonella enterica serovar Typhi (Ty2 aroC-ssaV-) M01ZH09, with a defined mutation in the Salmonella pathogenicity island 2, as a live, oral typhoid vaccine in human volunteers.

Kirkpatrick, B D; McKenzie, Robin; O'Neill, J Patrick; Larsson, Catherine J; Bourgeois, A Louis; Shimko, Janet; Bentley, Matthew; Makin, Jill; Chatfield, Steve; Hindle, Zoë; Fidler, Christine; Robinson, Brad E; Ventrone, Cassandra H; Bansal, Nivedita; Carpenter, Colleen M; Kutzko, Deborah; Hamlet, Sandra; LaPointe, Casey; Taylor, David N

Kirkpatrick, B D; McKenzie, Robin; O'Neill, J Patrick; Larsson, Catherine J; Bourgeois, A Louis; Shimko, Janet; Bentley, Matthew; Makin, Jill; Chatfield, Steve; Hindle, Zoë; Fidler, Christine; Robinson, Brad E; Ventrone, Cassandra H; Bansal, Nivedita; Carpenter, Colleen M; Kutzko, Deborah; Hamlet, Sandra; LaPointe, Casey; Taylor, David N.

Affiliation

Kirkpatrick BD; University of Vermont College of Medicine, Department of Medicine, Unit of Infectious Diseases, 95 Carrigan Drive, 110 Stafford Building, Burlington, VT 05405, USA. beth.kirkpatrick@uvm.edu

Vaccine ; 24(2): 116-23, 2006 Jan 12.

Article in En | MEDLINE | ID: mdl-16140433

Subject(s)

Mutation; Salmonella enterica/immunology; Typhoid-Paratyphoid Vaccines/immunology; Virulence/genetics; Administration, Oral; Adult; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Placebos; Salmonella enterica/genetics; Typhoid-Paratyphoid Vaccines/administration & dosage; Typhoid-Paratyphoid Vaccines/adverse effects

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Collection: 01-internacional Database: MEDLINE Main subject: Virulence / Typhoid-Paratyphoid Vaccines / Salmonella enterica / Mutation Type of study: Clinical_trials Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Vaccine Year: 2006 Type: Article Affiliation country: United States

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