Anthrabenzoxocinones from Streptomyces sp. as liver X receptor ligands and antibacterial agents.

Herath, Kithsiri B; Jayasuriya, Hiranthi; Guan, Ziqiang; Schulman, Marvin; Ruby, Carolyn; Sharma, Neelam; MacNaul, Karen; Menke, John G; Kodali, Srinivas; Galgoci, Andrew; Wang, Jun; Singh, Sheo B

Herath, Kithsiri B; Jayasuriya, Hiranthi; Guan, Ziqiang; Schulman, Marvin; Ruby, Carolyn; Sharma, Neelam; MacNaul, Karen; Menke, John G; Kodali, Srinivas; Galgoci, Andrew; Wang, Jun; Singh, Sheo B.

Affiliation

Herath KB; Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065, USA.

J Nat Prod ; 68(9): 1437-40, 2005 Sep.

Article in En | MEDLINE | ID: mdl-16180833

Subject(s)

Anti-Bacterial Agents/isolation & purification; DNA-Binding Proteins/metabolism; Heterocyclic Compounds, 4 or More Rings/isolation & purification; Receptors, Cytoplasmic and Nuclear/metabolism; Streptomyces/chemistry; Anthraquinones/isolation & purification; Anti-Bacterial Agents/chemistry; Anti-Bacterial Agents/pharmacology; Heterocyclic Compounds, 4 or More Rings/chemistry; Heterocyclic Compounds, 4 or More Rings/pharmacology; Inhibitory Concentration 50; Ligands; Liver X Receptors; Molecular Structure; Orphan Nuclear Receptors; Stereoisomerism

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Collection: 01-internacional Database: MEDLINE Main subject: Streptomyces / Receptors, Cytoplasmic and Nuclear / DNA-Binding Proteins / Heterocyclic Compounds, 4 or More Rings / Anti-Bacterial Agents Language: En Journal: J Nat Prod Year: 2005 Type: Article Affiliation country: United States

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