Nasal administration of carbamazepine using chitosan microspheres: in vitro/in vivo studies.

Gavini, E; Hegge, A B; Rassu, G; Sanna, V; Testa, C; Pirisino, G; Karlsen, J; Giunchedi, P

Gavini, E; Hegge, A B; Rassu, G; Sanna, V; Testa, C; Pirisino, G; Karlsen, J; Giunchedi, P.

Affiliation

Gavini E; Dipartimento di Scienze del Farmaco, University of Sassari, via Muroni 23/a, 07100 Sassari, Italy.

Int J Pharm ; 307(1): 9-15, 2006 Jan 03.

Article in En | MEDLINE | ID: mdl-16257156

Subject(s)

Anticonvulsants/administration & dosage; Anticonvulsants/pharmacokinetics; Carbamazepine/administration & dosage; Carbamazepine/pharmacokinetics; Drug Carriers; Microspheres; Nasal Mucosa/metabolism; Administration, Intranasal; Animals; Calorimetry, Differential Scanning; Carbamazepine/blood; Chitosan; Drug Carriers/chemical synthesis; Drug Compounding; Microscopy, Electron, Scanning; Particle Size; Sheep; Solubility

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Collection: 01-internacional Database: MEDLINE Main subject: Carbamazepine / Drug Carriers / Microspheres / Anticonvulsants / Nasal Mucosa Limits: Animals Language: En Journal: Int J Pharm Year: 2006 Type: Article Affiliation country: Italy

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