Postreplicative joining of DNA double-strand breaks causes genomic instability in DNA-PKcs-deficient mouse embryonic fibroblasts.

Martín, Marta; Genescà, Anna; Latre, Laura; Jaco, Isabel; Taccioli, Guillermo E; Egozcue, Josep; Blasco, María A; Iliakis, George; Tusell, Laura

Martín, Marta; Genescà, Anna; Latre, Laura; Jaco, Isabel; Taccioli, Guillermo E; Egozcue, Josep; Blasco, María A; Iliakis, George; Tusell, Laura.

Affiliation

Martín M; Department of Cell Biology, Physiology, and Immunology, Institute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona, Bellaterra, Spain.

Cancer Res ; 65(22): 10223-32, 2005 Nov 15.

Article in En | MEDLINE | ID: mdl-16288010

Subject(s)

DNA Repair/physiology; DNA-Activated Protein Kinase/deficiency; Fibroblasts/enzymology; Fibroblasts/ultrastructure; Genomic Instability/physiology; Animals; Cells, Cultured; Chromosome Aberrations/radiation effects; DNA Damage; DNA Replication; Embryo, Mammalian; Female; Fibroblasts/physiology; Fibroblasts/radiation effects; Genomic Instability/radiation effects; In Situ Hybridization, Fluorescence; Mice; Pregnancy; Sister Chromatid Exchange; Telomere/physiology

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Genomic Instability / DNA Repair / DNA-Activated Protein Kinase / Fibroblasts Type of study: Etiology_studies Limits: Animals / Pregnancy Language: En Journal: Cancer Res Year: 2005 Type: Article Affiliation country: Spain

Search on Google

XML

PubMed Links