Metallothionein expression in benign and malignant canine mammary gland tumours.
Res Vet Sci
; 81(1): 46-50, 2006 Aug.
Article
in En
| MEDLINE
| ID: mdl-16289156
ABSTRACT
The presence of metallothioneins (MTs) were demonstrated immunohistochemically using a monoclonal antibody (E9) against a conserved epitope of I and II isoforms in canine mammary tumours. In a semiquantitative analysis MT expression in the tumour cells was observed in 54/54 cases of benign and 32/40 malignant mammary neoplasms. A statistically significant difference at the level of P<0.01 was observed for MT expression between benign and malign mammary tumours in terms of immunoreactivity score. It is concluded that immunohistochemically demonstrated MT expression is significantly associated with benign canine mammary tumours.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Mammary Neoplasms, Animal
/
Dog Diseases
/
Metallothionein
Limits:
Animals
Language:
En
Journal:
Res Vet Sci
Year:
2006
Type:
Article
Affiliation country:
Turkey