Vasorelaxing effect of U50,488H in pulmonary artery and underlying mechanism in rats.

Sun, Xin; Ma, Sai; Zang, Yi-Min; Lu, Shun-Yan; Guo, Hai-Tao; Bi, Hui; Wang, Yue-Min; Ma, Heng; Ma, Xin-Liang; Pei, Jian-Ming

Sun, Xin; Ma, Sai; Zang, Yi-Min; Lu, Shun-Yan; Guo, Hai-Tao; Bi, Hui; Wang, Yue-Min; Ma, Heng; Ma, Xin-Liang; Pei, Jian-Ming.

Affiliation

Sun X; Department of Physiology, Fourth Military Medical University, Xi'an 710032, China.

Life Sci ; 78(21): 2516-22, 2006 Apr 18.

Article in En | MEDLINE | ID: mdl-16336977

Subject(s)

3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer/pharmacology; Antihypertensive Agents/pharmacology; Muscle, Smooth, Vascular/drug effects; Pulmonary Artery/drug effects; Adrenergic beta-Antagonists/pharmacology; Animals; Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Atropine/pharmacology; Dynorphins/pharmacology; Endothelium, Vascular/drug effects; Enzyme Inhibitors/pharmacology; In Vitro Techniques; Indomethacin/pharmacology; Male; Muscle Relaxation/drug effects; NG-Nitroarginine Methyl Ester/pharmacology; Nitric Oxide/physiology; Nitric Oxide Synthase Type III/antagonists & inhibitors; Peptide Fragments/pharmacology; Potassium Channel Blockers/pharmacology; Potassium Channels/physiology; Propranolol/pharmacology; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa/agonists

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Artery / 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer / Muscle, Smooth, Vascular / Antihypertensive Agents Limits: Animals Language: En Journal: Life Sci Year: 2006 Type: Article Affiliation country: China

Search on Google

XML

PubMed Links