Signaling through the murine T cell receptor induces IL-17 production in the absence of costimulation, IL-23 or dendritic cells.

Liu, Xikui K; Clements, James L; Gaffen, Sarah L

Liu, Xikui K; Clements, James L; Gaffen, Sarah L.

Affiliation

Liu XK; Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, Buffalo, NY 14214, USA.

Mol Cells ; 20(3): 339-47, 2005 Dec 31.

Article in En | MEDLINE | ID: mdl-16404147

Subject(s)

Dendritic Cells/physiology; Interleukin-17/biosynthesis; Interleukins/immunology; Receptors, Antigen, T-Cell/metabolism; Signal Transduction/physiology; T-Lymphocytes/immunology; Animals; CD28 Antigens/metabolism; CD3 Complex/pharmacology; Calcineurin/metabolism; Cyclosporine/pharmacology; Enzyme Inhibitors/pharmacology; Gene Expression Regulation/immunology; Humans; Interleukin-2/metabolism; Interleukin-2/pharmacology; Interleukin-23; Interleukin-23 Subunit p19; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases/metabolism; NFATC Transcription Factors/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Receptors, Antigen, T-Cell / T-Lymphocytes / Signal Transduction / Interleukins / Interleukin-17 Limits: Animals / Humans Language: En Journal: Mol Cells Journal subject: BIOLOGIA MOLECULAR Year: 2005 Type: Article Affiliation country: United States

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