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BTLA, a new inhibitory B7 family receptor with a TNFR family ligand.
Zeng, Chun; Wu, Tinghe; Zhen, Yu; Xia, Xue Pei; Zhao, Yong.
Affiliation
  • Zeng C; Transplantation Biology Research Division, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China.
Cell Mol Immunol ; 2(6): 427-32, 2005 Dec.
Article in En | MEDLINE | ID: mdl-16426492
ABSTRACT
B and T lymphocyte attenuator (BTLA), identified as an immune inhibitory receptor recently, plays widespread roles on T and B cells. Emerging evidence has generated plentiful information on the mechanisms which BTLA mediates negative regulation in immune responses and involves in a variety of physiological and pathological processes. The exploration of the biological mechanisms and regulation of BTLA will open possibilities on novel therapeutic strategies in immune-related diseases.
Subject(s)
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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Immunologic / Receptors, Tumor Necrosis Factor Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Mol Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2005 Type: Article Affiliation country: China
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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Immunologic / Receptors, Tumor Necrosis Factor Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Mol Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2005 Type: Article Affiliation country: China