Hypoxia-induced desensitization and internalization of adenosine A1 receptors in the rat hippocampus.

Coelho, J E; Rebola, N; Fragata, I; Ribeiro, J A; de Mendonça, A; Cunha, R A

Coelho, J E; Rebola, N; Fragata, I; Ribeiro, J A; de Mendonça, A; Cunha, R A.

Affiliation

Coelho JE; Laboratory of Neurosciences, Institute of Molecular Medicine, Faculty of Medicine, University of Lisbon, 1649-028 Lisboa, Portugal.

Neuroscience ; 138(4): 1195-203, 2006.

Article in En | MEDLINE | ID: mdl-16442739

Subject(s)

Endocytosis/physiology; Hippocampus/metabolism; Hypoxia-Ischemia, Brain/metabolism; Neural Inhibition/physiology; Presynaptic Terminals/metabolism; Receptor, Adenosine A1/metabolism; 2-Chloroadenosine/pharmacology; Adenosine/metabolism; Adenosine A1 Receptor Antagonists; Animals; Disease Models, Animal; Excitatory Postsynaptic Potentials/drug effects; Excitatory Postsynaptic Potentials/physiology; Hippocampus/physiopathology; Hypoxia-Ischemia, Brain/physiopathology; Male; Neural Inhibition/drug effects; Rats; Rats, Wistar; Synaptic Transmission/physiology; Theophylline/analogs & derivatives; Theophylline/pharmacology; Xanthines/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Presynaptic Terminals / Hypoxia-Ischemia, Brain / Receptor, Adenosine A1 / Endocytosis / Hippocampus / Neural Inhibition Limits: Animals Language: En Journal: Neuroscience Year: 2006 Type: Article Affiliation country: Portugal

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