Divalent metal transporter 1 in the kidney proximal tubule is expressed in late endosomes/lysosomal membranes: implications for renal handling of protein-metal complexes.

Abouhamed, Marouan; Gburek, Jakub; Liu, Wei; Torchalski, Blazej; Wilhelm, Andreas; Wolff, Natascha A; Christensen, Erik I; Thévenod, Frank; Smith, Craig P

Abouhamed, Marouan; Gburek, Jakub; Liu, Wei; Torchalski, Blazej; Wilhelm, Andreas; Wolff, Natascha A; Christensen, Erik I; Thévenod, Frank; Smith, Craig P.

Affiliation

Abouhamed M; Department of Physiology and Pathophysiology, Faculty of Medicine, Univ. of Witten/Herdecke, Witten, Germany.

Am J Physiol Renal Physiol ; 290(6): F1525-33, 2006 Jun.

Article in En | MEDLINE | ID: mdl-16449358

Subject(s)

Cation Transport Proteins/genetics; Endosomes/chemistry; Kidney Tubules, Proximal/ultrastructure; Kidney/metabolism; Lysosomes/chemistry; Metals/metabolism; Alternative Splicing; Animals; Cation Transport Proteins/analysis; Cation Transport Proteins/physiology; Cell Line, Transformed; Cells, Cultured; Fluorescent Antibody Technique; Gene Expression; Immunohistochemistry; Intracellular Membranes/chemistry; Kidney Cortex/chemistry; Male; Microscopy, Immunoelectron; RNA, Messenger/analysis; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Transferrin/analysis; Transferrin/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Endosomes / Cation Transport Proteins / Kidney / Kidney Tubules, Proximal / Lysosomes / Metals Limits: Animals Language: En Journal: Am J Physiol Renal Physiol Journal subject: FISIOLOGIA / NEFROLOGIA Year: 2006 Type: Article Affiliation country: Germany

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