PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection.

Pendaries, Caroline; Tronchère, Hélène; Arbibe, Laurence; Mounier, Joelle; Gozani, Or; Cantley, Lewis; Fry, Michael J; Gaits-Iacovoni, Frédérique; Sansonetti, Philippe J; Payrastre, Bernard

Pendaries, Caroline; Tronchère, Hélène; Arbibe, Laurence; Mounier, Joelle; Gozani, Or; Cantley, Lewis; Fry, Michael J; Gaits-Iacovoni, Frédérique; Sansonetti, Philippe J; Payrastre, Bernard.

Affiliation

Pendaries C; INSERM Unité 563, CPTP, Département d'Oncogenèse et Signalisation dans les Cellules Hématopoiétiques, Hôpital Purpan, Toulouse, France.

EMBO J ; 25(5): 1024-34, 2006 Mar 08.

Article in En | MEDLINE | ID: mdl-16482216

Subject(s)

Bacterial Proteins/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Phosphatidylinositol Phosphates/metabolism; Phosphoric Monoester Hydrolases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Shigella flexneri/pathogenicity; Signal Transduction; Animals; Bacterial Proteins/genetics; Cell Survival/drug effects; Cells, Cultured/drug effects; Cells, Cultured/metabolism; Cells, Cultured/microbiology; Fibroblasts/drug effects; Fibroblasts/metabolism; Fibroblasts/microbiology; HeLa Cells; Humans; Kidney/drug effects; Kidney/metabolism; Kidney/microbiology; Mice; Mice, Knockout; Mutation; Phosphoric Monoester Hydrolases/genetics; Phosphorylation/drug effects; Tyrosine/metabolism; Virulence

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Shigella flexneri / Bacterial Proteins / Signal Transduction / Phosphatidylinositol Phosphates / Phosphoric Monoester Hydrolases / Phosphatidylinositol 3-Kinases / Proto-Oncogene Proteins c-akt Limits: Animals / Humans Language: En Journal: EMBO J Year: 2006 Type: Article Affiliation country: France

Fulltext

XML

PubMed Links

Search on Google