Silencing of astrin induces the p53-dependent apoptosis by suppression of HPV18 E6 expression and sensitizes cells to paclitaxel treatment in HeLa cells.

Yang, Yuh-Cheng; Hsu, Yun-Ting; Wu, Chao-Chih; Chen, Hsiang-Ting; Chang, Mau-Sun

Yang, Yuh-Cheng; Hsu, Yun-Ting; Wu, Chao-Chih; Chen, Hsiang-Ting; Chang, Mau-Sun.

Affiliation

Yang YC; Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan.

Biochem Biophys Res Commun ; 343(2): 428-34, 2006 May 05.

Article in En | MEDLINE | ID: mdl-16546135

Subject(s)

Apoptosis/drug effects; Cell Cycle Proteins/metabolism; DNA-Binding Proteins/metabolism; Oncogene Proteins, Viral/metabolism; Paclitaxel/administration & dosage; Tumor Suppressor Protein p53/metabolism; Antineoplastic Agents/administration & dosage; Cell Cycle Proteins/genetics; DNA-Binding Proteins/genetics; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Silencing; HeLa Cells; Humans; Oncogene Proteins, Viral/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Oncogene Proteins, Viral / Tumor Suppressor Protein p53 / Paclitaxel / Apoptosis / Cell Cycle Proteins / DNA-Binding Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2006 Type: Article Affiliation country: Taiwan

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