Further validation of LABORAS using various dopaminergic manipulations in mice including MPTP-induced nigro-striatal degeneration.

Quinn, Leann P; Stean, Tania O; Chapman, Helen; Brown, Matthew; Vidgeon-Hart, Martin; Upton, Neil; Billinton, Andrew; Virley, David J

Quinn, Leann P; Stean, Tania O; Chapman, Helen; Brown, Matthew; Vidgeon-Hart, Martin; Upton, Neil; Billinton, Andrew; Virley, David J.

Affiliation

Quinn LP; Neurology & GI CEDD, GlaxoSmithKline Pharmaceuticals, Harlow, Essex CM19 5AW, UK. leann.p.quinn@gsk.com

J Neurosci Methods ; 156(1-2): 218-27, 2006 Sep 30.

Article in En | MEDLINE | ID: mdl-16626808

Subject(s)

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Behavior, Animal/drug effects; Dopamine Agents; Neostriatum/pathology; Nerve Degeneration/pathology; Psychology, Experimental/instrumentation; Substantia Nigra/pathology; Amphetamine/toxicity; Animals; Apomorphine/pharmacology; Automation; Benzazepines/pharmacology; Brain Chemistry/drug effects; Chromatography, High Pressure Liquid; Dopamine Agonists/pharmacology; Dopamine Antagonists/pharmacology; Dose-Response Relationship, Drug; Electrochemistry; Haloperidol/pharmacology; Hyperkinesis/chemically induced; Hyperkinesis/psychology; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Motor Activity/drug effects; Reproducibility of Results

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Psychology, Experimental / Behavior, Animal / Substantia Nigra / Dopamine Agents / 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine / Neostriatum / Nerve Degeneration Limits: Animals Language: En Journal: J Neurosci Methods Year: 2006 Type: Article Affiliation country: United kingdom

Search on Google

XML

PubMed Links