Improvement of glycemic control, triglycerides, and HDL cholesterol levels with muraglitazar, a dual (alpha/gamma) peroxisome proliferator-activated receptor activator, in patients with type 2 diabetes inadequately controlled with metformin monotherapy: A double-blind, randomized, pioglitazone-comparative study.

Kendall, David M; Rubin, Cindy J; Mohideen, Pharis; Ledeine, Jean-Marie; Belder, Rene; Gross, Jorge; Norwood, Paul; O'Mahony, Michael; Sall, Kenneth; Sloan, Greg; Roberts, Anthony; Fiedorek, Fred T; DeFronzo, Ralph A

Kendall, David M; Rubin, Cindy J; Mohideen, Pharis; Ledeine, Jean-Marie; Belder, Rene; Gross, Jorge; Norwood, Paul; O'Mahony, Michael; Sall, Kenneth; Sloan, Greg; Roberts, Anthony; Fiedorek, Fred T; DeFronzo, Ralph A.

Affiliation

Kendall DM; International Diabetes Center and the University of Minnesota, Minneapolis, Minnesota, USA.

Diabetes Care ; 29(5): 1016-23, 2006 May.

Article in En | MEDLINE | ID: mdl-16644631

Subject(s)

Blood Glucose/metabolism; Cholesterol, HDL/blood; Diabetes Mellitus, Type 2/drug therapy; Glycine/analogs & derivatives; Metformin/therapeutic use; Oxazoles/therapeutic use; Thiazolidinediones/therapeutic use; Triglycerides/blood; Adult; Diabetes Mellitus, Type 2/blood; Double-Blind Method; Female; Glycine/adverse effects; Glycine/therapeutic use; Humans; Hypoglycemic Agents/therapeutic use; Male; Middle Aged; Oxazoles/adverse effects; PPAR alpha/agonists; PPAR gamma/agonists; Pioglitazone; Thiazolidinediones/adverse effects

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Collection: 01-internacional Database: MEDLINE Main subject: Oxazoles / Triglycerides / Blood Glucose / Thiazolidinediones / Diabetes Mellitus, Type 2 / Glycine / Cholesterol, HDL / Metformin Type of study: Clinical_trials Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Diabetes Care Year: 2006 Type: Article Affiliation country: United States

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