Identification of novel target genes by an epigenetic reactivation screen of renal cancer.

Ibanez de Caceres, Inmaculada; Dulaimi, Essel; Hoffman, Amanda M; Al-Saleem, Tahseen; Uzzo, Robert G; Cairns, Paul

Ibanez de Caceres, Inmaculada; Dulaimi, Essel; Hoffman, Amanda M; Al-Saleem, Tahseen; Uzzo, Robert G; Cairns, Paul.

Affiliation

Ibanez de Caceres I; Departments of Surgical Oncology and Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA.

Cancer Res ; 66(10): 5021-8, 2006 May 15.

Article in En | MEDLINE | ID: mdl-16707423

Subject(s)

Carcinoma, Renal Cell/genetics; Gene Expression Regulation, Neoplastic; Kidney Neoplasms/genetics; Adult; Aged; Azacitidine/analogs & derivatives; Azacitidine/pharmacology; Base Sequence; Cell Line, Tumor; Collagen Type I/genetics; Collagen Type I, alpha 1 Chain; DNA Methylation; Decitabine; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Silencing; Humans; Hydroxamic Acids/pharmacology; Insulin-Like Growth Factor Binding Protein 1/genetics; Insulin-Like Growth Factor Binding Protein 3/genetics; Male; Middle Aged; Molecular Sequence Data; Promoter Regions, Genetic; RNA, Neoplasm/genetics; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Renal Cell / Gene Expression Regulation, Neoplastic / Kidney Neoplasms Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Cancer Res Year: 2006 Type: Article Affiliation country: United States

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