Gene transfer of cytidine deaminase protects myelopoiesis from cytidine analogs in an in vivo murine transplant model.

Rattmann, Ina; Kleff, Veronika; Sorg, Ursula R; Bardenheuer, Walter; Brueckner, Annette; Hilger, Ralf A; Opalka, Bertram; Seeber, Siegfried; Flasshove, Michael; Moritz, Thomas

Rattmann, Ina; Kleff, Veronika; Sorg, Ursula R; Bardenheuer, Walter; Brueckner, Annette; Hilger, Ralf A; Opalka, Bertram; Seeber, Siegfried; Flasshove, Michael; Moritz, Thomas.

Affiliation

Rattmann I; Department of Internal Medicine (Cancer Research), West German Cancer Center, University of Duisburg-Essen Medical School, Hufelandstr 55, 45122 Essen, Germany.

Blood ; 108(9): 2965-71, 2006 Nov 01.

Article in En | MEDLINE | ID: mdl-16835384

Subject(s)

Bone Marrow Transplantation/immunology; Cytarabine/toxicity; Cytidine Deaminase/genetics; Deoxycytidine/analogs & derivatives; 3T3 Cells; Animals; Bone Marrow Transplantation/mortality; Colony-Forming Units Assay; Cytidine Deaminase/metabolism; Deoxycytidine/toxicity; Gene Transfer Techniques; Graft Survival/physiology; Leukocyte Count; Mice; Models, Animal; Platelet Count; Recombinant Fusion Proteins/metabolism; Gemcitabine

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Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow Transplantation / Cytarabine / Cytidine Deaminase / Deoxycytidine Limits: Animals Language: En Journal: Blood Year: 2006 Type: Article Affiliation country: Germany

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