The quorum-sensing molecule N-3-oxododecanoyl homoserine lactone (3OC12-HSL) enhances the host defence by activating human polymorphonuclear neutrophils (PMN).

Wagner, Christof; Zimmermann, Sabine; Brenner-Weiss, Gerald; Hug, Friederike; Prior, Birgit; Obst, Ursula; Hänsch, Gertrud Maria

Wagner, Christof; Zimmermann, Sabine; Brenner-Weiss, Gerald; Hug, Friederike; Prior, Birgit; Obst, Ursula; Hänsch, Gertrud Maria.

Affiliation

Wagner C; Institut für Immunologie der Universität Heidelberg, Im Neuenheimer Feld 305, 69120, Heidelberg, Germany.

Anal Bioanal Chem ; 387(2): 481-7, 2007 Jan.

Article in En | MEDLINE | ID: mdl-16906383

Subject(s)

4-Butyrolactone/analogs & derivatives; Bacteria/immunology; Homoserine/analogs & derivatives; Immunity; Neutrophil Activation/immunology; Quorum Sensing; 4-Butyrolactone/immunology; 4-Butyrolactone/pharmacology; Bacteria/chemistry; Bacteria/pathogenicity; Biofilms; Cell Communication/immunology; Cells, Cultured; Chemotaxis, Leukocyte/drug effects; Chemotaxis, Leukocyte/immunology; Homoserine/immunology; Homoserine/pharmacology; Humans; Immunity/drug effects; Phagocytosis; Pseudomonas aeruginosa/immunology; Pseudomonas aeruginosa/pathogenicity; Receptors, Immunologic/genetics; Up-Regulation/genetics; Up-Regulation/immunology

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / 4-Butyrolactone / Neutrophil Activation / Quorum Sensing / Homoserine / Immunity Limits: Humans Language: En Journal: Anal Bioanal Chem Year: 2007 Type: Article Affiliation country: Germany

Search on Google

XML

PubMed Links