MAPK-specific tyrosine phosphatases: new targets for drug discovery?

Barr, Alastair J; Knapp, Stefan

Barr, Alastair J; Knapp, Stefan.

Affiliation

Barr AJ; Structural Genomics Consortium, University of Oxford, Botnar Research Centre, Oxford, OX3 7LD, UK. alastair.barr@sgc.ox.ac.uk

Trends Pharmacol Sci ; 27(10): 525-30, 2006 Oct.

Article in En | MEDLINE | ID: mdl-16919785

Subject(s)

Drug Design; Mitogen-Activated Protein Kinase Kinases; Protein Tyrosine Phosphatases; Animals; Crystallography, X-Ray; Humans; Mitogen-Activated Protein Kinase Kinases/chemistry; Mitogen-Activated Protein Kinase Kinases/metabolism; Mitogen-Activated Protein Kinase Kinases/physiology; Models, Molecular; Phosphorylation; Protein Tyrosine Phosphatases/chemistry; Protein Tyrosine Phosphatases/metabolism; Protein Tyrosine Phosphatases/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Protein Tyrosine Phosphatases / Mitogen-Activated Protein Kinase Kinases Limits: Animals / Humans Language: En Journal: Trends Pharmacol Sci Year: 2006 Type: Article Affiliation country: United kingdom

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