Mitogen-activated protein kinase-mediated disruption of enhancer-promoter communication inhibits hepatocyte nuclear factor 4alpha expression.

Hatzis, Pantelis; Kyrmizi, Irene; Talianidis, Iannis

Hatzis, Pantelis; Kyrmizi, Irene; Talianidis, Iannis.

Affiliation

Hatzis P; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Herakleion, Crete, Greece.

Mol Cell Biol ; 26(19): 7017-29, 2006 Oct.

Article in En | MEDLINE | ID: mdl-16980607

Subject(s)

Enhancer Elements, Genetic/genetics; Hepatocyte Nuclear Factor 4/genetics; Hepatocyte Nuclear Factor 4/metabolism; Mitogen-Activated Protein Kinase 1/metabolism; Promoter Regions, Genetic/genetics; Acetylation/drug effects; CCAAT-Enhancer-Binding Protein-alpha/deficiency; CCAAT-Enhancer-Binding Protein-alpha/genetics; Cells, Cultured; DNA Helicases; Down-Regulation/drug effects; Enzyme Activation/drug effects; Hepatocyte Nuclear Factor 4/deficiency; Histones/metabolism; Humans; Models, Genetic; Nuclear Proteins/metabolism; RNA Interference; RNA Polymerase II/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Signal Transduction/drug effects; Tetradecanoylphorbol Acetate/pharmacology; Transcription Factors/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enhancer Elements, Genetic / Promoter Regions, Genetic / Mitogen-Activated Protein Kinase 1 / Hepatocyte Nuclear Factor 4 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Biol Year: 2006 Type: Article Affiliation country: Greece

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