Thymidine kinase mutations conferring acyclovir resistance in herpes simplex type 1 recombinant viruses.

Sergerie, Yan; Boivin, Guy

Sergerie, Yan; Boivin, Guy.

Affiliation

Sergerie Y; CHUQ-CHUL, room RC-709, 2705, blvd Laurier, Sainte-Foy, Québec, Canada.

Antimicrob Agents Chemother ; 50(11): 3889-92, 2006 Nov.

Article in En | MEDLINE | ID: mdl-16982796

Subject(s)

Acyclovir/pharmacology; Antiviral Agents/pharmacology; Herpesvirus 1, Human/drug effects; Thymidine Kinase/genetics; Animals; Chlorocebus aethiops; Cosmids/genetics; DNA, Viral/genetics; DNA-Directed DNA Polymerase/genetics; Genotype; Kinetics; Mutation/genetics; Phenotype; Plasmids/genetics; Vero Cells; Virus Replication/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Thymidine Kinase / Acyclovir / Herpesvirus 1, Human Limits: Animals Language: En Journal: Antimicrob Agents Chemother Year: 2006 Type: Article Affiliation country: Canada

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