A novel method for analysis of single ion channel signal based on wavelet transform.
Comput Biol Med
; 37(4): 559-62, 2007 Apr.
Article
in En
| MEDLINE
| ID: mdl-16996492
ABSTRACT
A single ion channel signal was analysed by the power distribution fraction constructed by a discrete wavelet transform. Average opening time and energy distribution of the signal can be obtained directly by this method. The method can also be used when the signal is corrupted by noise. By contrast, the conventional frequency domain analysis method--power spectral density--is less effective. Power distribution fraction will therefore give more useful information in analysis of experimental ion channel signals, principally by giving values of the mean channel opening time. The method may be applied to distinguish different ion channels more efficiently and to find their reactions to drugs.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Signal Processing, Computer-Assisted
/
Fourier Analysis
/
Ion Channels
Limits:
Humans
Language:
En
Journal:
Comput Biol Med
Year:
2007
Type:
Article
Affiliation country:
China