Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma.

Burgermeister, Elke; Chuderland, Dana; Hanoch, Tamar; Meyer, Markus; Liscovitch, Mordechai; Seger, Rony

Burgermeister, Elke; Chuderland, Dana; Hanoch, Tamar; Meyer, Markus; Liscovitch, Mordechai; Seger, Rony.

Affiliation

Burgermeister E; Department of Biological Regulation, The Weizmann Institute of Science, Rehovot 76100, Israel.

Mol Cell Biol ; 27(3): 803-17, 2007 Feb.

Article in En | MEDLINE | ID: mdl-17101779

Subject(s)

Cell Nucleus/metabolism; Down-Regulation; MAP Kinase Kinase 1/metabolism; MAP Kinase Kinase 2/metabolism; PPAR gamma/metabolism; Active Transport, Cell Nucleus/drug effects; Acyl-CoA Oxidase/genetics; Animals; CHO Cells; COS Cells; Cell Nucleus/drug effects; Chlorocebus aethiops; Cricetinae; Cricetulus; Cytosol/drug effects; Down-Regulation/drug effects; HeLa Cells; Humans; Mitogen-Activated Protein Kinase 3/metabolism; PPAR gamma/genetics; Protein Binding/drug effects; Protein Structure, Tertiary/drug effects; Protein Transport/drug effects; Rats; Rosiglitazone; Serine/metabolism; Tetradecanoylphorbol Acetate/pharmacology; Thiazolidinediones/pharmacology; Transcriptional Activation/drug effects; Two-Hybrid System Techniques

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Down-Regulation / Cell Nucleus / MAP Kinase Kinase 1 / MAP Kinase Kinase 2 / PPAR gamma Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Mol Cell Biol Year: 2007 Type: Article Affiliation country: Israel

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