Plasma RNA as an alternative to cells for monitoring molecular response in patients with chronic myeloid leukemia.

Ma, Wanlong; Tseng, Richard; Gorre, Mercedes; Jilani, Iman; Keating, Michael; Kantarjian, Hagop; Cortes, Jorge; O'Brien, Susan; Giles, Francis; Albitar, Maher

Ma, Wanlong; Tseng, Richard; Gorre, Mercedes; Jilani, Iman; Keating, Michael; Kantarjian, Hagop; Cortes, Jorge; O'Brien, Susan; Giles, Francis; Albitar, Maher.

Affiliation

Ma W; Quest Diagnostics Nichols Institute 33608 Ortega Highway, Rm#108B, San Juan Capistrano, CA 92690-6130, USA.

Haematologica ; 92(2): 170-5, 2007 Feb.

Article in En | MEDLINE | ID: mdl-17296565

Subject(s)

Leukemia, Myelogenous, Chronic, BCR-ABL Positive/blood; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/therapy; Monitoring, Physiologic/methods; RNA/blood; RNA/genetics; Antineoplastic Agents/therapeutic use; Benzamides; Case-Control Studies; DNA Primers/chemistry; Fusion Proteins, bcr-abl/blood; Fusion Proteins, bcr-abl/genetics; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics; Piperazines/therapeutic use; Pyrimidines/therapeutic use; RNA, Messenger/metabolism; RNA, Neoplasm/metabolism; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: RNA / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Monitoring, Physiologic Type of study: Observational_studies Limits: Humans Language: En Journal: Haematologica Year: 2007 Type: Article Affiliation country: United States

Search on Google

XML

PubMed Links