Fatal and widespread skeletal myopathy confirmed morphologically years after initiation of simvastatin therapy.

Boltan, David Demitry; Lachar, Whitney; Khetan, Anita; Bouffard, John-Paul; Roberts, William Clifford

Boltan, David Demitry; Lachar, Whitney; Khetan, Anita; Bouffard, John-Paul; Roberts, William Clifford.

Affiliation

Boltan DD; Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas 75205, USA.

Am J Cardiol ; 99(8): 1171-6, 2007 Apr 15.

Article in En | MEDLINE | ID: mdl-17437752

Subject(s)

Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects; Hypolipidemic Agents/adverse effects; Muscular Diseases/chemically induced; Simvastatin/adverse effects; Calcinosis/pathology; Deglutition Disorders/chemically induced; Dysarthria/chemically induced; Dyspnea/chemically induced; Fatal Outcome; Fibrosis; Humans; Male; Middle Aged; Muscle Fibers, Skeletal/pathology; Muscle Weakness/chemically induced; Muscular Diseases/pathology; Necrosis

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Collection: 01-internacional Database: MEDLINE Main subject: Hydroxymethylglutaryl-CoA Reductase Inhibitors / Simvastatin / Muscular Diseases / Hypolipidemic Agents Limits: Humans / Male / Middle aged Language: En Journal: Am J Cardiol Year: 2007 Type: Article Affiliation country: United States

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