Behavioral phenotypes of Disc1 missense mutations in mice.

Clapcote, Steven J; Lipina, Tatiana V; Millar, J Kirsty; Mackie, Shaun; Christie, Sheila; Ogawa, Fumiaki; Lerch, Jason P; Trimble, Keith; Uchiyama, Masashi; Sakuraba, Yoshiyuki; Kaneda, Hideki; Shiroishi, Toshihiko; Houslay, Miles D; Henkelman, R Mark; Sled, John G; Gondo, Yoichi; Porteous, David J; Roder, John C

Clapcote, Steven J; Lipina, Tatiana V; Millar, J Kirsty; Mackie, Shaun; Christie, Sheila; Ogawa, Fumiaki; Lerch, Jason P; Trimble, Keith; Uchiyama, Masashi; Sakuraba, Yoshiyuki; Kaneda, Hideki; Shiroishi, Toshihiko; Houslay, Miles D; Henkelman, R Mark; Sled, John G; Gondo, Yoichi; Porteous, David J; Roder, John C.

Affiliation

Clapcote SJ; Samuel Lunenfeld Research Institute at Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada. mail.steve@btinternet.com

Neuron ; 54(3): 387-402, 2007 May 03.

Article in En | MEDLINE | ID: mdl-17481393

Subject(s)

Behavior, Animal/physiology; Mice, Mutant Strains/physiology; Mutation, Missense/genetics; Nerve Tissue Proteins/genetics; Phenotype; 3',5'-Cyclic-AMP Phosphodiesterases/metabolism; Alanine/genetics; Animals; Behavior, Animal/drug effects; Brain/anatomy & histology; Cyclic Nucleotide Phosphodiesterases, Type 4; DNA Mutational Analysis/methods; Female; Glutamine/genetics; Humans; Leucine/genetics; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains/anatomy & histology; Neural Inhibition/genetics; Protein Binding/genetics; Reflex, Acoustic/genetics; Subcellular Fractions/metabolism; Threonine/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Phenotype / Behavior, Animal / Mutation, Missense / Mice, Mutant Strains / Nerve Tissue Proteins Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Neuron Journal subject: NEUROLOGIA Year: 2007 Type: Article Affiliation country: Canada

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