Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism.

Pirinen, Eija; Kuulasmaa, Teemu; Pietilä, Marko; Heikkinen, Sami; Tusa, Maija; Itkonen, Paula; Boman, Susanna; Skommer, Joanna; Virkamäki, Antti; Hohtola, Esa; Kettunen, Mikko; Fatrai, Szabolcs; Kansanen, Emilia; Koota, Suvi; Niiranen, Kirsi; Parkkinen, Jyrki; Levonen, Anna-Liisa; Ylä-Herttuala, Seppo; Hiltunen, J Kalervo; Alhonen, Leena; Smith, Ulf; Jänne, Juhani; Laakso, Markku

Pirinen, Eija; Kuulasmaa, Teemu; Pietilä, Marko; Heikkinen, Sami; Tusa, Maija; Itkonen, Paula; Boman, Susanna; Skommer, Joanna; Virkamäki, Antti; Hohtola, Esa; Kettunen, Mikko; Fatrai, Szabolcs; Kansanen, Emilia; Koota, Suvi; Niiranen, Kirsi; Parkkinen, Jyrki; Levonen, Anna-Liisa; Ylä-Herttuala, Seppo; Hiltunen, J Kalervo; Alhonen, Leena; Smith, Ulf; Jänne, Juhani; Laakso, Markku.

Affiliation

Pirinen E; Department of Medicine, University of Kuopio, P.O. Box 1777, FI-70211 Kuopio, Finland.

Mol Cell Biol ; 27(13): 4953-67, 2007 Jul.

Article in En | MEDLINE | ID: mdl-17485446

Subject(s)

Adipose Tissue, White/growth & development; Energy Metabolism; Glucose/metabolism; Homeostasis; Polyamines/metabolism; AMP-Activated Protein Kinases; Acetyltransferases/metabolism; Adenosine Triphosphate/metabolism; Adipocytes/drug effects; Adipocytes/metabolism; Adipose Tissue, White/cytology; Adipose Tissue, White/drug effects; Adipose Tissue, White/enzymology; Animals; Body Composition/drug effects; Energy Metabolism/drug effects; Feeding Behavior/drug effects; Fibroblasts/drug effects; Fibroblasts/metabolism; Food Deprivation; Gene Expression Regulation, Enzymologic/drug effects; Glucose Intolerance; Homeostasis/drug effects; Hydrogen Peroxide/pharmacology; Isoenzymes/genetics; Isoenzymes/metabolism; Macrophages/cytology; Macrophages/drug effects; Macrophages/metabolism; Mice; Mitochondria/drug effects; Mitochondria/metabolism; Multienzyme Complexes/genetics; Multienzyme Complexes/metabolism; Organ Size/drug effects; Oxidative Phosphorylation/drug effects; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation/drug effects; Protein Serine-Threonine Kinases/genetics; Protein Serine-Threonine Kinases/metabolism; Trans-Activators/genetics; Trans-Activators/metabolism; Transcription Factors; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyamines / Energy Metabolism / Adipose Tissue, White / Glucose / Homeostasis Type of study: Health_economic_evaluation / Prognostic_studies Language: En Journal: Mol Cell Biol Year: 2007 Type: Article Affiliation country: Finland

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