HIF-1 alpha expression is associated with an atheromatous inflammatory plaque phenotype and upregulated in activated macrophages.

Vink, Aryan; Schoneveld, Arjan H; Lamers, Dennis; Houben, Anna J S; van der Groep, Petra; van Diest, Paul J; Pasterkamp, Gerard

Vink, Aryan; Schoneveld, Arjan H; Lamers, Dennis; Houben, Anna J S; van der Groep, Petra; van Diest, Paul J; Pasterkamp, Gerard.

Affiliation

Vink A; Department of Pathology, University Medical Center Utrecht, Ultrecht, The Netherlands. a.vink@umcutrecht.nl

Atherosclerosis ; 195(2): e69-75, 2007 Dec.

Article in En | MEDLINE | ID: mdl-17606258

Subject(s)

Carotid Artery Diseases/metabolism; Foam Cells/metabolism; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; Macrophages/metabolism; Animals; Carotid Artery Diseases/physiopathology; Cells, Cultured; Endarterectomy, Carotid; Femoral Artery/metabolism; Femoral Artery/pathology; Fibroblasts/metabolism; Humans; Immunohistochemistry; Mice; Monocytes, Activated Killer/metabolism; Neovascularization, Pathologic/metabolism; Phenotype; Up-Regulation; Vascular Endothelial Growth Factor A/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Carotid Artery Diseases / Hypoxia-Inducible Factor 1, alpha Subunit / Foam Cells / Macrophages Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Atherosclerosis Year: 2007 Type: Article Affiliation country: Netherlands

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