Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma.

Moffatt, Miriam F; Kabesch, Michael; Liang, Liming; Dixon, Anna L; Strachan, David; Heath, Simon; Depner, Martin; von Berg, Andrea; Bufe, Albrecht; Rietschel, Ernst; Heinzmann, Andrea; Simma, Burkard; Frischer, Thomas; Willis-Owen, Saffron A G; Wong, Kenny C C; Illig, Thomas; Vogelberg, Christian; Weiland, Stephan K; von Mutius, Erika; Abecasis, Gonçalo R; Farrall, Martin; Gut, Ivo G; Lathrop, G Mark; Cookson, William O C

Moffatt, Miriam F; Kabesch, Michael; Liang, Liming; Dixon, Anna L; Strachan, David; Heath, Simon; Depner, Martin; von Berg, Andrea; Bufe, Albrecht; Rietschel, Ernst; Heinzmann, Andrea; Simma, Burkard; Frischer, Thomas; Willis-Owen, Saffron A G; Wong, Kenny C C; Illig, Thomas; Vogelberg, Christian; Weiland, Stephan K; von Mutius, Erika; Abecasis, Gonçalo R; Farrall, Martin; Gut, Ivo G; Lathrop, G Mark; Cookson, William O C.

Affiliation

Moffatt MF; National Heart and Lung Institute, Imperial College, London SW3 6LY, UK.

Nature ; 448(7152): 470-3, 2007 Jul 26.

Article in En | MEDLINE | ID: mdl-17611496

Subject(s)

Asthma/genetics; Gene Expression Regulation/genetics; Genetic Predisposition to Disease; Membrane Proteins/genetics; Polymorphism, Single Nucleotide/genetics; Age of Onset; Asthma/epidemiology; Case-Control Studies; Child; Chromosomes, Human, Pair 17/genetics; Germany; Humans; RNA, Messenger/genetics; RNA, Messenger/metabolism; United Kingdom

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Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Gene Expression Regulation / Genetic Predisposition to Disease / Polymorphism, Single Nucleotide / Membrane Proteins Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Child / Humans Country/Region as subject: Europa Language: En Journal: Nature Year: 2007 Type: Article Affiliation country: United kingdom

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