DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection.

Walker, Mark J; Hollands, Andrew; Sanderson-Smith, Martina L; Cole, Jason N; Kirk, Joshua K; Henningham, Anna; McArthur, Jason D; Dinkla, Katrin; Aziz, Ramy K; Kansal, Rita G; Simpson, Amelia J; Buchanan, John T; Chhatwal, Gursharan S; Kotb, Malak; Nizet, Victor

Walker, Mark J; Hollands, Andrew; Sanderson-Smith, Martina L; Cole, Jason N; Kirk, Joshua K; Henningham, Anna; McArthur, Jason D; Dinkla, Katrin; Aziz, Ramy K; Kansal, Rita G; Simpson, Amelia J; Buchanan, John T; Chhatwal, Gursharan S; Kotb, Malak; Nizet, Victor.

Affiliation

Walker MJ; School of Biological Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.

Nat Med ; 13(8): 981-5, 2007 Aug.

Article in En | MEDLINE | ID: mdl-17632528

Subject(s)

Deoxyribonuclease I/metabolism; Streptococcal Infections/microbiology; Streptococcus pyogenes/enzymology; Streptococcus pyogenes/pathogenicity; Animals; Cell Survival; Deoxyribonuclease I/genetics; Humans; Immunity, Innate; Mice; Neutrophils/cytology; Neutrophils/microbiology; Phenotype; Selection, Genetic; Streptococcal Infections/pathology; Streptococcus pyogenes/genetics; Virulence

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Collection: 01-internacional Database: MEDLINE Main subject: Streptococcal Infections / Streptococcus pyogenes / Deoxyribonuclease I Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2007 Type: Article Affiliation country: Australia

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