Down-regulation of the sodium/iodide symporter explains 131I-induced thyroid stunning.

Nordén, Madeleine M; Larsson, Fredrik; Tedelind, Sofia; Carlsson, Therese; Lundh, Charlotta; Forssell-Aronsson, Eva; Nilsson, Mikael

Nordén, Madeleine M; Larsson, Fredrik; Tedelind, Sofia; Carlsson, Therese; Lundh, Charlotta; Forssell-Aronsson, Eva; Nilsson, Mikael.

Affiliation

Nordén MM; Department of Medical Chemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy at Göteborg University, Sweden. madeleine.norden@anatcell.gu.se

Cancer Res ; 67(15): 7512-7, 2007 Aug 01.

Article in En | MEDLINE | ID: mdl-17671222

Subject(s)

Iodine Radioisotopes/adverse effects; Radiation Injuries/etiology; Symporters/metabolism; Thyroid Diseases/etiology; Thyroid Gland/radiation effects; Animals; Down-Regulation; Insulin-Like Growth Factor I/pharmacology; RNA, Messenger/genetics; RNA, Messenger/metabolism; Radiation Injuries/prevention & control; Radionuclide Imaging; Reverse Transcriptase Polymerase Chain Reaction; Swine; Symporters/antagonists & inhibitors; Symporters/genetics; Thyroid Diseases/diagnostic imaging; Thyroid Diseases/prevention & control; Thyroid Gland/diagnostic imaging; Thyroid Gland/injuries; Thyrotropin/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Radiation Injuries / Thyroid Diseases / Thyroid Gland / Symporters / Iodine Radioisotopes Limits: Animals Language: En Journal: Cancer Res Year: 2007 Type: Article Affiliation country: Sweden

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