Pharmacokinetic modelling of interleukin-1 receptor antagonist in plasma and cerebrospinal fluid of patients following subarachnoid haemorrhage.

Gueorguieva, Ivelina; Clark, Simon R; McMahon, Catherine J; Scarth, Sylvia; Rothwell, Nancy J; Tyrrell, Pippa J; Tyrell, Pippa J; Hopkins, Stephen J; Rowland, Malcolm

Gueorguieva, Ivelina; Clark, Simon R; McMahon, Catherine J; Scarth, Sylvia; Rothwell, Nancy J; Tyrrell, Pippa J; Tyrell, Pippa J; Hopkins, Stephen J; Rowland, Malcolm.

Affiliation

Gueorguieva I; Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, UK. gueorguieva_ivelina@lilly.com

Br J Clin Pharmacol ; 65(3): 317-25, 2008 Mar.

Article in En | MEDLINE | ID: mdl-17875190

Subject(s)

Interleukin 1 Receptor Antagonist Protein/pharmacokinetics; Models, Biological; Subarachnoid Hemorrhage/blood; Subarachnoid Hemorrhage/cerebrospinal fluid; Adult; Aged; Female; Humans; Interleukin 1 Receptor Antagonist Protein/blood; Interleukin 1 Receptor Antagonist Protein/cerebrospinal fluid; Male; Middle Aged; Subarachnoid Hemorrhage/drug therapy; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Subarachnoid Hemorrhage / Interleukin 1 Receptor Antagonist Protein / Models, Biological Type of study: Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Br J Clin Pharmacol Year: 2008 Type: Article Affiliation country: United kingdom

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