A novel nonobese diabetic/severe combined immunodeficient xenograft model for chronic lymphocytic leukemia reflects important clinical characteristics of the disease.

Dürig, Jan; Ebeling, Peter; Grabellus, Florian; Sorg, Ursula R; Möllmann, Michael; Schütt, Philipp; Göthert, Joachim; Sellmann, Ludger; Seeber, Siegfried; Flasshove, Michael; Dührsen, Ulrich; Moritz, Thomas

Dürig, Jan; Ebeling, Peter; Grabellus, Florian; Sorg, Ursula R; Möllmann, Michael; Schütt, Philipp; Göthert, Joachim; Sellmann, Ludger; Seeber, Siegfried; Flasshove, Michael; Dührsen, Ulrich; Moritz, Thomas.

Affiliation

Dürig J; Department of Hematology, University of Duisburg-Essen Medical School, Essen, Germany.

Cancer Res ; 67(18): 8653-61, 2007 Sep 15.

Article in En | MEDLINE | ID: mdl-17875705

Subject(s)

Disease Models, Animal; Leukemia, Lymphocytic, Chronic, B-Cell/pathology; Adult; Aged; Aged, 80 and over; Animals; Cell Growth Processes/physiology; Female; Humans; Male; Mice; Mice, Inbred NOD; Mice, SCID; Middle Aged; Neoplasm Transplantation; Reproducibility of Results; Risk Factors; Spleen/pathology; T-Lymphocytes/pathology; Transplantation, Heterologous

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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Disease Models, Animal Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: Cancer Res Year: 2007 Type: Article Affiliation country: Germany

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