A large animal model to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma.

Varela, Mariana; Golder, Matthew; Archer, Fabienne; de las Heras, Marcelo; Leroux, Caroline; Palmarini, Massimo

Varela, Mariana; Golder, Matthew; Archer, Fabienne; de las Heras, Marcelo; Leroux, Caroline; Palmarini, Massimo.

Affiliation

Varela M; Institute of Comparative Medicine, University of Glasgow Veterinary School, 464 Bearsden Road, Glasgow, G61 1QH, Scotland, UK.

Virology ; 371(1): 206-15, 2008 Feb 05.

Article in En | MEDLINE | ID: mdl-17961623

Subject(s)

Adenocarcinoma/therapy; Disease Models, Animal; HSP90 Heat-Shock Proteins/antagonists & inhibitors; HSP90 Heat-Shock Proteins/therapeutic use; Lung Neoplasms/therapy; Sheep, Domestic; Adenocarcinoma/metabolism; Adenocarcinoma/virology; Animals; Cell Line, Transformed; Cell Transformation, Viral; Drug Evaluation, Preclinical; Immunohistochemistry; Jaagsiekte sheep retrovirus; Lung Neoplasms/metabolism; Lung Neoplasms/virology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenocarcinoma / HSP90 Heat-Shock Proteins / Sheep, Domestic / Disease Models, Animal / Lung Neoplasms Limits: Animals Language: En Journal: Virology Year: 2008 Type: Article Affiliation country: United kingdom

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