Peripheral TNFalpha, but not peripheral IL-1, requires endogenous IL-1 or TNFalpha induction in the brain for the febrile response.

Chida, Dai; Iwakura, Yoichiro

Chida, Dai; Iwakura, Yoichiro.

Affiliation

Chida D; Division of Cell Biology, Center for Experimental Medicine, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

Biochem Biophys Res Commun ; 364(4): 765-70, 2007 Dec 28.

Article in En | MEDLINE | ID: mdl-17967442

Subject(s)

Brain/drug effects; Brain/immunology; Fever/chemically induced; Fever/immunology; Interleukin-1/immunology; Interleukin-6/immunology; Tumor Necrosis Factor-alpha; Animals; Body Temperature Regulation/drug effects; Body Temperature Regulation/immunology; Dose-Response Relationship, Drug; Mice; Mice, Knockout

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Collection: 01-internacional Database: MEDLINE Main subject: Brain / Interleukin-6 / Interleukin-1 / Tumor Necrosis Factor-alpha / Fever Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2007 Type: Article Affiliation country: Japan

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