Efficient systemic expression of bioactive IL-15 in mice upon delivery of optimized DNA expression plasmids.

Jalah, Rashmi; Rosati, Margherita; Kulkarni, Viraj; Patel, Vainav; Bergamaschi, Cristina; Valentin, Antonio; Zhang, Gen-Mu; Sidhu, Maninder K; Eldridge, John H; Weiner, David B; Pavlakis, George N; Felber, Barbara K

Jalah, Rashmi; Rosati, Margherita; Kulkarni, Viraj; Patel, Vainav; Bergamaschi, Cristina; Valentin, Antonio; Zhang, Gen-Mu; Sidhu, Maninder K; Eldridge, John H; Weiner, David B; Pavlakis, George N; Felber, Barbara K.

Affiliation

Jalah R; Human Retrovirus Pathogenesis Section, Vaccine Branch, National Cancer Institute-Frederick, Frederick, Maryland 21702-1201, USA. felber@ncifcrf.gov

DNA Cell Biol ; 26(12): 827-40, 2007 Dec.

Article in En | MEDLINE | ID: mdl-17979522

Subject(s)

Interleukin-15/biosynthesis; Interleukin-15/genetics; Amino Acid Sequence; Animals; Female; Gene Expression; Genetic Vectors; Humans; Interleukin-15/blood; Macaca mulatta; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Muscles/metabolism; Plasmids/administration & dosage; Plasmids/genetics; Protein Sorting Signals/genetics; RNA Processing, Post-Transcriptional; RNA, Messenger/genetics; RNA, Messenger/metabolism; Recombinant Proteins/biosynthesis; Recombinant Proteins/blood; Recombinant Proteins/genetics; Sequence Homology, Amino Acid

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Collection: 01-internacional Database: MEDLINE Main subject: Interleukin-15 Limits: Animals / Female / Humans Language: En Journal: DNA Cell Biol Journal subject: BIOLOGIA MOLECULAR Year: 2007 Type: Article Affiliation country: United States

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