The G2 p38-mediated stress-activated checkpoint pathway becomes attenuated in transformed cells.

Mikhailov, Alexei; Patel, Daksha; McCance, Dennis J; Rieder, Conly L

Mikhailov, Alexei; Patel, Daksha; McCance, Dennis J; Rieder, Conly L.

Affiliation

Mikhailov A; Laboratory of Cell Regulation, Division of Molecular Medicine, New York State Department of Health, Wadsworth Center, P.O. Box 509, Albany, New York 12201-0509, USA.

Curr Biol ; 17(24): 2162-8, 2007 Dec 18.

Article in En | MEDLINE | ID: mdl-18060783

Subject(s)

Cell Transformation, Neoplastic/metabolism; G2 Phase/physiology; Mitosis/physiology; p38 Mitogen-Activated Protein Kinases/metabolism; Extracellular Signal-Regulated MAP Kinases/metabolism; HeLa Cells; Humans; Retinoblastoma Protein/metabolism; Stress, Physiological/metabolism; ras Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Transformation, Neoplastic / G2 Phase / P38 Mitogen-Activated Protein Kinases / Mitosis Limits: Humans Language: En Journal: Curr Biol Journal subject: BIOLOGIA Year: 2007 Type: Article Affiliation country: United States

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